Faculty Sponsor

Jana Stedman

College

College of Nursing & Health Professions (CONHP)

Department/Program

MSPA Program

Presentation Type

Poster Presentation

Symposium Date

7-23-2025

Abstract

Objective: The purpose of this research investigation is to evaluate the impact of intermittent fasting on glycemic control in patients with prediabetes or metabolic syndrome.

Methods: A structured literature review was conducted using Google Scholar to identify relevant studies published within the last five years. Search terms included "Insulin Resistance, Intermittent Fasting," "Prediabetes, Intermittent Fasting," and "Intermittent Fasting, Metabolic Syndrome." Inclusion criteria were English-language, full-text articles focusing on intermittent fasting interventions in populations with prediabetes or metabolic syndrome. Studies were excluded if they were published more than five years ago, focused solely on weight loss, or included participants already diagnosed with type 2 diabetes mellitus. Outcomes of interest included fasting glucose, fasting insulin, HbA1c, and insulin resistance measured by the Homeostatic Model Assessment of Insulin Resistance (HOMA-IR).

Results: Intermittent fasting, whether by alternate day fasting or time restricted feeding, resulted in a statistically significant impact on fasting glucose and HOMA-IR consistently. There were no adverse effects identified due to the intervention.

Conclusion: Intermittent fasting appears to be a safe and effective strategy to enhance insulin sensitivity and improve glycemic control in individuals with prediabetes or metabolic syndrome. However, further longitudinal studies are needed to assess the sustainability and long-term metabolic effects of intermittent fasting in these populations.

Keywords: intermittent fasting, insulin resistance, prediabetes, metabolic syndrome, hba1c, fasting glucose, homa-ir

Biographical Information about Author(s)

Caitlin Malon is a graduating Physician Assistant student who has a special interest in Urology and plans on working in that field. She will be presenting on the “Effects of Intermittent Fasting on Glycemic Markers in Patients with Insulin Resistance” because she has an interest in attainable lifestyle interventions for the prevention of type 2 diabetes mellitus.

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