Faculty Sponsor

Jana Stedman

College

Nursing

Department/Program

Physician Assistant Program

Presentation Type

Poster Presentation

Symposium Date

Summer 7-24-2024

Abstract

Objective: The primary goal of this literature review is to assess the recurrence rate of basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) after micrographically oriented histographic surgery (MOHS) compared to the recurrence rate of BCC and SCC following superficial radiation therapy (SRT), using data gathered from multiple clinical studies.

Methods: Search engines used included Google Scholar, Pub Med, Valpo Summon, and UpToDate. The inclusion criteria set stated the studies should be within 5 years, meta-analysis, retrospective cohort studies, cross-sectional studies, adult participants, and non-melanoma skin cancer. Exclusion criteria included those with diagnoses other than BCC or SCC, as well as no evidence of regional lymph node metastasis. Four retrospective cohort studies and 1 prospective cohort study were included. The endpoints of interest include recurrence rates of BCC/SCC using MOHS, recurrence rates of BCC/SCC using SRT treatment, cure rates using MOHS, and cure rates using SRT. The secondary endpoints include survival rates of BCC/SCC after either treatment, as well as cosmetic results.

Results: The recurrence rate over at least a year ranged from 1.9%-7.3% using MOHs, and 0.7-2.1% using SRT treatment.

Conclusion: The overall recurrence rates of both BCC and SCC using either MOHS or SRT are relatively equal. The decision to use either treatment modality can be a provider-patient individualized decision.

Key Words: MOHS, SRT, non-melanoma skin cancer, recurrence rates, efficacy, squamous cell carcinoma, and basal cell carcinoma.

Biographical Information about Author(s)

Jillian Wilder has a special interest in Dermatology and plans on pursuing a career within that field. She will be presenting on " Micrographically Oriented Histographic Surgery Versus Superficial Radiation Therapy in the Treatment of Basal Cell and Squamous Cell Carcinoma" because she is interested in prevention, early detection, and treatment of skin cancers.

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