Antipsychotic Drug Use in Elderly Patients with Dementia

Faculty Sponsor

Jana Steadman

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College

Nursing

Department/Program

Physician Assistant Program

Presentation Type

Poster Presentation

Symposium Date

Summer 7-24-2024

Abstract

Objective: The objective of this paper is to determine if antipsychotic (AP) drug usage in the elderly population, specifically with elderly who have dementia, has a significant effect on the morbidity and mortality of this select population.

Methods: In this paper the articles included: 2 meta-analysis, 1 prospective cohort, 1 matched cohort study, 1 randomized control trial, and a systematic review that included studies about patients using AP drugs, and studies with patients with dementia.

Results: AP drug use in the elderly population, specifically in those with dementia, has an overall increased mortality rate and an increased possibility of adverse events. Risperidone has the highest risk out of all AP drugs, and quetiapine has the lowest risk.

Conclusion: Administration of AP drugs in patients with dementia have an increased effect on their morbidity and mortality, it would be wise for providers to explore non-pharmacological treatments for BPSD management.

Keywords: Dementia, antipsychotic drugs, mortality, morbidity, behavioral and psychological symptoms of dementia.

Biographical Information about Author(s)

Molly Fisher has a special interest in primary care and plans on working in Indianapolis, Indiana following graduation. She will be presenting on “Antipsychotic Drug Use in Elderly Patients with Dementia,” because she has a special interest in treating elderly patients with multiple comorbid conditions affecting their health outcomes and quality of life.

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