Faculty Sponsor

Jana Stedman

College

Nursing

Department/Program

Physician Assistant

Presentation Type

Poster Presentation

Symposium Date

Summer 7-24-2024

Abstract

Objective: To evaluate the efficacy and safety of the Watchman device in patients with atrial fibrillation, specifically proving the prevention or reduction of major complications when compared to anticoagulant use. Major complications can include thrombotic events which can consist of stroke, clinically relevant bleeding, and device related thrombi.

Methods: Research was conducted in reviewing studies consisting of two meta-analyses, one systematic review, and two randomized controlled trials. These studies needed to include the use of the Watchman device being compared to different types of anticoagulants in patients with atrial fibrillation. In total, twenty research studies were reviewed and five were chosen. Research studies needed to be after 2018 and peer-reviewed to be considered. Primary endpoints included risk of stroke, all cause mortality, and cardiovascular mortality. Secondary endpoints included clinically relevant bleeding and device related thrombi.

Results: The use of the Watchman provided promising results in being safe, effective, and viable option for patients with atrial fibrillation who are not able to tolerate anticoagulant therapy. The risk of thrombotic events in the Watchman device is comparable to anticoagulant therapy and in some cases a better long term option.

Conclusion: The Watchman device is a promising alternative compared to the mainstay treatment of anticoagulant therapy in patients with atrial fibrillation. Since this device is not a first line treatment, more research should be done to build up a solid foundation on the long term safety and efficacy of the device.

Keywords: watchman procedure, atrial fibrillation, anticoagulant therapy, left atrial appendage, thrombotic events

Download

Share

COinS