The Effects of Subclinical Hypothyroidism

Faculty Sponsor

Jana Stedman

College

Nursing

Department/Program

Master of Science in Physician Assistant Studies

Presentation Type

Poster Presentation

Symposium Date

Summer 7-24-2024

Abstract

Objectives: Subclinical hypothyroidism (SCH) is defined as an elevated thyroid-stimulating hormone (TSH) with normal thyroxine (T4) levels, and there are multiple opinions on the benefits of treatment for increasing quality of life, decreasing neuropsychiatric symptoms, decreasing cardiovascular events, and decreasing mortality risks in those diagnosed with the condition. However, there is not much consolidated data or general overview of its potential benefits. This paper summarizes the impact of thyroid hormone therapy and the effects of being untreated for those with subclinical hypothyroidism. Methods: Valparaiso Summons and PubMed were the two research databases that were used to find the five articles that were utilized in this paper regarding the outcomes of treatment in SCH. Data was limited to the last eight years. Results: Treating subclinical hypothyroidism in those less than 65 years of age was found to decrease all-cause mortality while treatment in those greater than 65 years of age did not show as much benefit. Thyroid-related symptoms were not resolved with treatment in those with subclinical hypothyroidism aged 32 and older. Conclusions: There needs to be further research regarding cardiovascular disease risk and treatment in those who are older than 65 years of age, but treatment is overall beneficial in decreasing all-cause mortality in those less than 65 years of age.

Keywords: subclinical hypothyroidism, mortality, cardiovascular events, cardiovascular disease, thyroid-related symptoms, quality of life

Biographical Information about Author(s)

Renee was inspired to research The Effects of Subclinical Hypothyroidism because she is interested in various thyroid conditions and when treatment is most beneficial. Her other interests include running, hiking, and being with family and friends. Currently, she is a student member of Indiana Academy of Physician Assistants (IAPA) and American Academy of Physician Associates (AAPA) and the Valparaiso University Physician Assistant Student Society (VUPASS). She thanks her professors and preceptors for the education she has received and her growth in clinical practice.

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