Current principles for the surgical treatment of intrahepatic cholangiocarcinoma

Authors

Catalin Savin, Carol Davila University of Medicine and Pharmacy, Bucharest, RomaniaFollow
Luiza Tarca, Carol Davila University of Medicine and Pharmacy, Bucharest, RomaniaFollow
Irina Balescu, Carol Davila University of Medicine and Pharmacy, Bucharest, RomaniaFollow
Sorin Petrea, Carol Davila University of Medicine and Pharmacy, Bucharest, RomaniaFollow
Bogdan Gaspar, Carol Davila University of Medicine and Pharmacy, Bucharest, RomaniaFollow
Lucian Pop, Carol Davila University of Medicine and Pharmacy, Bucharest, RomaniaFollow
Valentin Varlas, Carol Davila University of Medicine and PharmacyFollow
Adrian Hasegan, University of Sibiu, Faculty of Medicine, Sibiu Emergency Hospital, Department of Urology, Sibiu, RomaniaFollow
Gabriel Petre Gorecki, Titu Maiorescu University, CF-2 Clinical Hospital, Department of Anesthesia and Intensive Care, Bucharest, RomaniaFollow
Cristina Martac, Fundeni Clinical Hospital, Department of Anesthesiology, Bucharest, RomaniaFollow
Marilena Stoian, Carol Davila University of Medicine and Pharmacy, Bucharest, RomaniaFollow
Cristian Balalau, Carol Davila University of Medicine and Pharmacy, Bucharest, RomaniaFollow
Nicolae Bacalbasa, Carol Davila University of Medicine and PharmacyFollow

Abstract

Intrahepatic cholangiocarcinoma is one of the most aggressive forms of cancer. It is usually diagnosed in advanced stages of the disease, mainly because it is asymptomatic for a long time after the onset. Consequently, intrahepatic cholangiocarcinoma still represents an important problem of diagnosis and treatment. In the multidisciplinary treatment of these patients, oncological surgery is essential, as the accuracy of resection is one of the most important prognostic factors for the long-term results of these patients. Therefore, there has been a continuing concern to improve surgical techniques, with the aim of maximizing the chances of achieving the best possible long-term survival. The purpose of this paper is to discuss the surgical standard of care in intrahepatic cholangiocarcinoma, with particular attention being paid to resection margins and lymph node dissection. For unresectable cholangiocarcinoma, locoregional therapy can be used such as transarterial chemoembolization, transarterial radioembolization, thermal ablation, radiotherapy and hepatic artery infusion pump chemotherapy.

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Recommended Citation

Savin, Catalin; Tarca, Luiza; Balescu, Irina; Petrea, Sorin; Gaspar, Bogdan; Pop, Lucian; Varlas, Valentin; Hasegan, Adrian; Gorecki, Gabriel Petre; Martac, Cristina; Stoian, Marilena; Balalau, Cristian; and Bacalbasa, Nicolae (2024) "Current principles for the surgical treatment of intrahepatic cholangiocarcinoma," Journal of Mind and Medical Sciences: Vol. 11: Iss. 2, Article 7.
DOI: https://doi.org/10.22543/2392-7674.1502
Available at: https://scholar.valpo.edu/jmms/vol11/iss2/7