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Authors

Ana Maria Dascalu, CAROL DAVILA University of Medicine and PharmacyFollow
Sanda Jurja, Ovidius University ConstantaFollow
Carmen Luminita Mocanu, University of Medicine and Pharmacy Craiova, RomaniaFollow
Cristina Alexandrescu, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy Bucharest, Ophthalmology Department, Emergency University Hospital BucharestFollow
Daniela Stana, Emergency University Hospital BucharestFollow
Madalina Totir, Carol Davila University of Medicine and Pharmacy BucharestFollow
Ece Ergin, Emergency University Hospital BucharestFollow
Corneliu Tudor, Faculty of Medicine, CAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY, Fourth Gewrenral Surgery Department, EMERGENCY UNIVERSITY HOSPITAL BUCHAREST, ROMANIAFollow
Catalin Cicerone Grigorescu, Faculty of Medicine, Titu Maiorescu University Bucharest, RomaniaFollow
Dragos Serban, CAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY, EMERGENCY UNIVERSITY HOSPITAL BUCHAREST, DEPARTMENT OF GENERAL SURGERY, BUCHAREST, ROMANIAFollow
Laurentiu Simion, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy Bucharest, Ophthalmology Department, Emergency University Hospital BucharestFollow
Dan Dumitrescu, Carol Davila University of Medicine and Pharmacy, Faculty of General Medicine, Bucharest, RomaniaFollow
Andrei Marin, Carol Davila University of Medicine and Pharmacy BucharestFollow
Catalin Teodor Constantinescu, Emergency County Hospital Pitesti, RomaniaFollow
Bogdan Mihai Cristea, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy Bucharest, RomaniaFollow

Abstract

Endophthalmitis incidence and clinical characteristics was reported to change during Covid-19 pandemic, due to multiple influencing factors, such as prolonged lockdown periods, persistent immune suppression following Sars-Cov-2 infection, and mask wearing. We conducted a retrospective eight-year study, during January 2016 and December 2023, that aims to investigates the differences in terms of etiology, clinical characteristics and outcomes in cases with acute endophthalmitis, admitted before (2016-2019) and during Covid-19 pandemic (2020-2023). The two study subgroups were homogenous in term of age, gender distribution, associated comorbidities, and addressability. During Covid-19 pandemic there were significant delays in presentation (p=0.02), more cases of endogenous endophthalmitis (p=0.025), and patients presented a more intense systemic inflammatory reaction (p

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