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Alina Doina Nicoara, Faculty of Medicine, “Ovidius” University of Constanta, 1 Universitatii Street, 900470 Constanta, Romania2. Internal Medicine Department, “Sf. Apostol Andrei” Emergency County Hospital, 145 Tomis Blvd., 900591 Constanta, RomaniaFollow
Andra Iulia Suceveanu, Faculty of Medicine, “Ovidius” University of Constanta, 1 Universitatii Street, 900470 Constanta, Romania3. Gastroenterology Department, “Sf. Apostol Andrei” Emergency County Hospital, 145 Tomis Blvd., 900591 Constanta, RomaniaFollow
Ionut Eduard Iordache, Ovidius University, Faculty of Medicine, 1 Universitatii Street, 900470 Constanta, Romania, 1st General Surgery Department, Emergency Clinical St Apostle Andrew, ConstantaHospitalFollow
Iulia Tania Andronache, Rheumatology Department, Internal Medicine Clinic, “Dr. Alexandru Gafencu” Military Emergency Hospital Constanta, 900527 Constanta, RomaniaFollow
Andreea Nelson Twakor, Internal Medicine Department, “Sf. Apostol Andrei” Emergency County Hospital, 145 Tomis Blvd., 900591 Constanta, RomaniaFollow
Andreea Georgiana Sunda, Internal Medicine Department, “Sf. Apostol Andrei” Emergency County Hospital, 145 Tomis Blvd., 900591 Constanta, RomaniaFollow
Ioan Cristian Nichita, Internal Medicine Department, “Sf. Apostol Andrei” Emergency County Hospital, 145 Tomis Blvd., 900591 Constanta, RomaniaFollow
Anca Pantea Stoian, Diabetes, nutrition and metabolic disorders Department, “Carol Davila” University of Medicine and Farmacy, 37 Dionisie Lupu, 20021 Bucharest, RomaniaFollow
Felix Voinea, 8. Ovidius University, Faculty of Medicine, Urology Department, “Sf. Apostol Andrei” Emergency County Hospital, 145 Tomis Blvd., 900591 Constanta, RomaniaFollow
Adrian Paul Suceveanu, Faculty of Medicine, “Ovidius” University of Constanta, 1 Universitatii Street, 900470 Constanta, Romania, Gastroenterology Department, “Sf. Apostol Andrei” Emergency County Hospital, 145 Tomis Blvd, 900591 Constanta, RomaniaFollow

Abstract

Managing anticoagulation therapy in individuals with atrial fibrillation who also have liver disease is highly challenging due to altered blood clotting processes and the risk of bleeding due to liver dysfunction. The literature highlights the complex nature of anticoagulant therapy in these patients, emphasizing the need for personalized treatment methods that take into account both thrombosis and bleeding risks. Research has shown a higher occurrence of atrial fibrillation in people with cirrhosis, highlighting the need to find the best anticoagulation methods based on the severity of liver disease and patient-specific factors. The debate over the safety and effectiveness of direct oral anticoagulants compared to traditional drugs like warfarin in cirrhotic patients with atrial fibrillation is still ongoing. Collaborative initiatives between experts in hepatology and cardiology are needed to address the complicated interplay between liver disease and atrial fibrillation, promoting interdisciplinary care models that enhance patient safety and treatment effectiveness. By prioritizing a patient-centered approach guided by extensive research, future directions in the hemostatic management of cirrhotic patients with atrial fibrillation may improve clinical decision-making and therapeutic outcomes.

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Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.

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