Diabetic Foot Ulcers and Hyperbaric Oxygen Treatment
Master's of Physician Assistant Studies Program
Objective: Diabetic foot ulcers are a commonly occurring condition in patients with diabetes. They are often difficult to treat and may result in adverse events including serious infection and need for amputation. The objective of the study was to assess the efficacy of hyperbaric oxygen therapy (HBOT) for wound healing in patients with diabetic foot ulcers compared to standard treatment. Methods: To determine the best method of treatment in adults, a search was conducted through the Valparaiso University online library catalog utilizing peer-reviewed articles regarding treatment of diabetic foot ulcers with HBOT within the last ten years. Results: The following outcomes were included; Complete healing of ulcers, minor amputation, major amputation, all group amputation, ulcer reduction area, mortality rate, adverse events, and factor for predicting success. Conclusions: Adjunctive treatment of diabetic foot ulcers with HBOT resulted in significantly better complete wound healing and lowered rates of major amputation. However, minor amputation and all group amputation does not seem to be improved with HBOT. Reduction in ulcer size, quality of life, mortality rate was not found to be significant when comparing treatments. Several multiple adverse events were reported with HPOT however most resolved without sequela. Lastly, there do not seem to be factors that may influence outcomes of therapy, but HBOT may have potential to reduce anxiety and pain.
Keywords: diabetic foot ulcers, hyperbaric oxygen therapy treatment, complete ulcer healing, major amputation, minor amputation, quality of life, mortality rate, adverse events predictors for success
Sobieski, Libbie, "Diabetic Foot Ulcers and Hyperbaric Oxygen Treatment" (2023). Summer Interdisciplinary Research Symposium. 154.