Physician Assistant Graduate Program
Objective: To compare the efficacy, safety, cost, and time of thermal ablation techniques versus a thyroidectomy for benign and malignant thyroid nodules.
Methods: This research was conducted using EBSCO Host, PubMed, the American Thyroid Association, and NYU Langone Health. 15 studies were reviewed that met the defined criteria. Types of studies included were metanalyses/systemic reviews, retrospective studies, case presentations, and prospective randomized studies. Primary endpoints include efficacy, safety, cost, and time.
Results: For benign nodules, radiofrequency ablation (RFA) has advantages over a thyroidectomy due to it being effective, minimally invasive, safe, economical, and cosmetically appealing. For malignant nodules, RFA is seen to be effective for low-risk papillary thyroid cancer only. Regarding the type of ablation technique, RFA is considered superior due to greater efficacy and reoccurrence rates.
Conclusions: RFA is an effective, safe, and low-cost alternative to a thyroidectomy for benign nodules and low risk papillary thyroid cancer.
Keywords: benign thyroid nodules, malignant thyroid nodules, thyroid nodule treatment, thyroidectomy, endoscopic thyroidectomy, ablation techniques, and radiofrequency ablation.
Valente, Emily, "Comparison of Thermal Ablation and Thyroidectomy for Thyroid Nodules" (2023). Summer Interdisciplinary Research Symposium. 149.