The Link Between Antihypertensive Agents and Cognitive Decline

Faculty Sponsor

Theresa Kessler




Health Sciences/Physician Assistant Studies

Presentation Type

Poster Presentation

Symposium Date

Spring 5-3-2018


By the year 2020, 42 million individuals are expected to suffer from dementia. A curative treatment for the disease has not yet been developed which stresses the importance of managing modifiable risk factors. Given that dementia has been linked to hypertension in elderly patients, a plethora of research has examined the relationship between antihypertensive agents and cognitive decline (Andrieu et al., 2015). The purpose of this project was to provide an answer for the following focused clinical question: in elderly patients with hypertension, how does the use of antihypertensive agents influence cognitive decline and the onset of dementia? A search for literature was conducted with the use of five databases (Cochrane Library, National Guideline Clearinghouse, PubMed, MEDLINE, and CINAHL). The search yielded one systematic review, two meta-analyses, one integrated review, one randomized control trial, one cohort study, and one review article. Findings that work to answer the focused clinical question will be presented.

Biographical Information about Author(s)

Kayleigh Corn, Alyson Kinzie, and Luke Stanczyk are members of the physician assistant program. They are in their third year of the program and are anticipating graduating this May with an undergraduate degree in Health Sciences before moving on to the graduate phase of the program.

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